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What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect

Non-invasive: No needles or clinical appointments required

Mobile IV therapy makes sense for individuals who value convenience, privacy or recovery at home

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

Self-experimentation is not the same thing as clinician-guided care

5-Amino-1MQ Peptide Therapy Procedure 1