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Subjects were randomized to lixisenatide 10 mcg/d (up- or down-titrated to max 20 mcg/d) or placebo

No published clinical human trial demonstrating measurable GLP-1 level changes from this specific product is known to this publication

Two patients can be on the same dose, in the same program, and see different results

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Spectra were background-corrected by subtraction of the spectrum obtained in the presence of microsomes and NADPH, respectively intact HepG, but in absence of NFT