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The evidence: True mechanism, often hyped marketing
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Drug interaction warnings that may not be immediately obvious
Coolican et al
Retatrutide, a triple-agonist (GLP-1, GIP and glucagon), is in late-stage trials and has produced even more weight loss in early data up to 24% at 48 weeks in phase 2
While similar GI symptoms may occur with oral anti-diabetic agents, such as metformin and alpha glucosidase inhibitors (flatulence, diarrhea and pain), symptoms improve when the medication is discontinued [68]
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