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Review Article: Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity Background More than 19 years after the first GLP1RA was introduced for type 2 diabetes and 10 years after its approval for obesity, innovations are expanding the use of GLP-1 medicines for metabolic disorders

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Therefore, refraining from alcohol helps to minimise these risks and ensures a safer and more effective treatment outcome

Energy improvements from GLP-1 therapy typically develop gradually over weeks to months as blood glucose stabilises and weight loss occurs, rather than immediately

As the body adapts to the medications effects on appetite and digestion, symptoms usually become less frequent and less intense

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