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In one study, participants who consumed a spermidine-rich diet for 3 months exhibited improved insulin sensitivity and lower fasting glucose levels, suggesting spermidines potential as a therapeutic agent for managing metabolic disorders (Reference Wirth, Benson and Schwarz99)

Inspect the solution if it appears cloudy, discoloured, or contains visible particles, do not use it

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Patients should be advised to maintain adequate fluid intake, particularly during dose escalation

However, adding B12 without a documented deficiency offers no proven benefit and represents unnecessary cost and injection frequency