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It was through that experience, and the conversations that followed about her skin, that she first learned about GLP-1 medications
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It mimics a natural hormone that reduces appetite, improves blood sugar, and slows digestion
For microdosing specifically, clinical practitioners report that patients with RA who cannot tolerate or do not qualify for full-dose GLP-1 therapy are seeing meaningful reductions in morning stiffness, flare frequency, and body aches at microdose levels
In addition, GLP-1R stimulation activates insulin signaling pathways and regulates gene expression, decreasing systemic insulin resistance and brain insulin resistance in patients with AD (Dahiya et al., 2025)
Areas typically treated with injectables include the temples, areas around the eyes, the cheeks, lips, and jawline
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