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Epithalon (also known as Epitalon) is a synthetic tetrapeptide used in laboratory research on cellular aging
However, the researchers studied pancreatic tissue taken from mice and humans of different ages, body weights, and diabetes statuses, and analyzed it using a specially developed high-specificity mass spectrometry assay that can detect only the bioactive form of GLP-1
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Study has demonstrated that GSDMD mediates the shift of tubular cells from apoptosis to pyroptosis in TLR4-regulated diabetic tubular damage, suggesting that GSDMD activation promotes the conversion from non-inflammatory apoptosis to inflammatory pyroptosis (227)
