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B 42 GaiC.LiuC.WuX.YuM.ZhengJ.ZhangW.et al (2020)

However, use of strong oxidizing agents and reactive intermediates like aldehyde generated in the preparation process necessitate an optimized purification procedure to avoid possible associated toxicity

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Fourth, although the study leveraged a large and diverse U.S.-based population, findings may not be generalizable to other healthcare systems or regions with different prescribing patterns and surveillance intensity