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Civil Engineering, UCLA Last updated: July 2026 Human-researched and AI-assisted with full editorial review
It is estimated that vitamin B12 deficiency affects up to 15 percent of the population in the United States
While oral supplements may be effective for some, the bodys ability to absorb them often decreases with age
B12 Shots & B12 Injections: The Good, Bad and Alternative
intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies
Do not use B12 injections if you are currently pregnant, breastfeeding or plan to become pregnant or breastfeed
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