Dilatative Kardiomyopathie (DCM) - Welsh Springer Spaniel globo-product-options Mutation: P3H2 gene

Mutation: P3H2 gene

Clinical signs of affected puppies are deafness assessed by abnormal behaviour or by BAER (brainstem auditory evoked response) examinations

swollen lymph nodes

Affected dogs are usually euthanized at an early age due to poor prognosis

In French bulldog two variants in two different genes (TYRP1 and HPS3) were associated with brown coat color

Dilatative Kardiomyopathie (DCM) - Welsh Springer Spaniel globo-product-options Mutation: P3H2 geneDilated Cardiomyopathy (DCM) is a hereditary disease known in animals and humans with many similarities including familial nature, clinical signs and phenotypic features. It is characterised by cardiac enlargement (cardiomegaly) and decreased myocardial function. Due to heart arrhythmias affected individuals suffer from heart failure or collapse. The symptoms in dogs usually occur 20 months postnatal and include ventricular dilation, systolic