Neuronale Zeroidlipofuszinose 12 (NCL-12) - Australian Cattle Dog Mischling Acepromazine

Acepromazine

Histopathologische Untersuchungen zeigen eine Spaltung der Epidermis von der darunterliegenden Dermis innerhalb oder direkt unterhalb der Basalmembran

Neutrophils are phagocytes

Dog is homozygous for uniform coat coloration in pigmented areas

leading to progressive kidney failure

Neuronale Zeroidlipofuszinose 12 (NCL-12) - Australian Cattle Dog Mischling AcepromazineNeuronal ceroid lipofuscinosis is a lysosomal storage disease, characterized by neurodegeneration and decline in neurological functions at approximately 6 years of age due to accumulation of autofluorescent lysosomal storage bodies in cells of the central nervous system, as well as many other tissues. The clinical signs also include anxiety, impaired ability to recognize and respond to previously learned commands, increased sensitivity to loud or