Osteogenesis Imperfecta (OI) - Beagle Startseite Affected dogs experience unpredictable seizures

Affected dogs experience unpredictable seizures with increased aggression

giving an overall comma-like morphology to the body

are characterised by distinctive morphological traits including a wide head

schlafend oder unter Allgemeinanästhesie sind

healthy life for your dog with additional tests

Osteogenesis Imperfecta (OI) - Beagle Startseite Affected dogs experience unpredictable seizuresOsteogenesis imperfecta is an autosomal dominant disease caused by a mutation in the COLA2 gene, which encodes collagen. Mutations altering the sequence can lead to disruptions of the collagen structure, which can lead to abnormally brittle bones that fracture very easily. The disease can be found in several dog breeds. The affected newborn puppies are exposed to fractures affecting almost every long bone right after birth and often have to be