X-chromosomal Myotubuläre Myopathie (XL-MTM) - Labrador Retriever ISAG Mutation: AGL-Gen

Mutation: AGL-Gen

and therefore they transmit mutated gene to their offspring

hyperextension of the limbs

Sie wird durch anatomische Anomalien im Gehirn beschrieben - ein kleineres oder nicht entwickeltes Kleinhirn

Junctional epidermolysis bullosa (JEB) is an autosomal recessive disorder belonging in a group of congenital blistering skin diseases

X-chromosomal Myotubuläre Myopathie (XL-MTM) - Labrador Retriever ISAG Mutation: AGL-GenMyotubular myopathy is a X linked recessive disorder. Affected infant male puppies show signs of facial, axial and proximal neuromuscular weakness with tetraparesis, difficulty holding the head up and a dropped jaw, including hypotonia and areflexia leading to respiratory insufficiency and death within 2 weeks. The symptoms usually occur postnatal and progress very quickly. The affected male puppies have to be euthanised due to progressive symptoms.