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Canine multifocal retinopathy (CMR1) is an autosomal recessive genetic eye disorder similar to Best macular dystrophy in humans
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Even dogs that are double cryptic merle (Mc/Mc) can look inconspicuously like non-merle dogs
Mutation: SLC25A12 gene
and permanently accessible
Kongenitaler Idiopathischer Megaösophagus (CIM) ISAG Canine multifocal retinopathy (CMR1) isCongenital idiopathic megaesophagus (CIM) is a motility disorder of oesophagus preventing the normal transport of food to the stomach due to reduced peristaltic activity and dilation. Affected dogs show regurgitation of food and water, cough and complications such as aspiration pneumonia, excessive salivation, mild to moderate cachexia and pulmonary crackles or wheezes. A normal oesophagus contracts to allow the passage of food into the stomach. In
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